Genetic information contained within DNA has to be read by specific proteins that enable the process of gene activation to begin – but in many cases, these proteins can’t access their targets because DNA strands are bundled up to control what genes are used in the wide range of different cell types.
New research led by scientists at The Ohio State University shows how one of these proteins, known as a transcription factor, functions as a special “pioneer factor” by managing to bind to a blocked segment of DNA to begin the process of opening up and activating a gene.
Reposted from news.osu.edu
